Comparison between eicosapentaenoic acid (EPA)
and docosahexaenoic acid (DHA) |
|
EPA |
DHA |
• Greater reduction in hs-CRP |
• Longer hydrocarbon length, promoting conformational changes in
the membrane of vascular smooth muscle cells and macrophages |
• Inhibits oxidation of ApoB-containing particles |
• Increases LDL-C levels |
• Greater induction of nitric oxide release |
• Does not decrease ApoB levels |
• Greater lowering of linoleic and arachidonic acid plasma
levels |
• Favors reduction of platelet aggregation in females |
• Induces endothelium-dependent vasorelaxation and enhances
endothelial function |
• Greater anti-thrombotic effect |
• Favours reduction of platelet aggregation in males |
• Greater increase in adiponectin levels [unclear relevance] |
Abbreviations
Reference
Quispe et al.: Controversies in the Use of Omega-3 Fatty Acids to Prevent Atherosclerosis. Curr Atheroscler Rep. 2022 Jul;24(7):571-581. doi: 10.1007/s11883-022-01031-9. Epub 2022 Apr 30.
Also see ...
- Vegans with high blood triglycerides might benefit from EPA supplements
- Nutrient recommendations for vegans
- Vegan EPA only supplements